Both the brain and the immune system begin their journey with a learning process, directly linked to the environmental settings, to ultimately generate memory and execute effector functions; many of these functions control body homeostasis and are co-regulated throughout life. The implication of immune regulation in many disorders is thus a fast-emerging field as it holds a great promise in disease prevention, early diagnosis and treatment. Studies in my laboratory focus on exploring the interactions between the brain and the immune system from early development to aging. Our ultimate goal is to provide better tools to fight autoimmune, psychiatric and neurodegenerative diseases, conditions with ever-growing social and financial costs.