{"id":4067,"date":"2020-12-02T20:45:32","date_gmt":"2020-12-02T20:45:32","guid":{"rendered":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/?page_id=4067"},"modified":"2026-01-03T22:06:28","modified_gmt":"2026-01-03T22:06:28","slug":"publications","status":"publish","type":"page","link":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"
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  1. Weight loss aggravates obesity-induced hypothalamic inflammation in mid-aged mice. Zemer A et al., Geroscience. 2025 Oct 17. doi: 10.1007\/s11357-025-01933-x2.<\/span><\/a><\/li>\n
  2. CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging. Elyahu Y et al, Nat Aging. 2025 Oct;5(10):1970-1982. doi: 10.1038\/s43587-025-00953-8.<\/span><\/a><\/li>\n
  3. CD4 T-cell aging exacerbates neuroinflammation in a late-onset mouse model of amyotrophic lateral sclerosis.\u00a0 <\/span><\/a>Zaccai S et al., J Neuroinflammation. 2024 Jan 11;21(1):17.\u00a0<\/span><\/li>\n
  4. Brain-immune axis regulation is responsive to cognitive behavioral therapy and mindfulness intervention: Observations from a randomized controlled trial in patients with Crohn’s disease.\u00a0 <\/span><\/a>Nemirovsky A. et al., Brain Behav Immun Health. 2021 Dec 23;19:100407.\u00a0<\/span><\/li>\n
  5. Thymus involution sets the clock of the aging T-cell landscape: Implications for declined immunity and tissue repair.\u00a0 <\/span><\/a>Elyahu Y, Monsonego A. Ageing Res Rev. 2021 Jan;65:101231. Review.\u00a0<\/span><\/li>\n
  6. Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes.\u00a0 <\/span><\/a>Elyahu Y & Hekselman I et al., Sci Adv. 2019 Aug 21;5(8):eaaw8330.\u00a0<\/span><\/li>\n
  7. CD4\u00a0T Cells Induce A Subset of MHCII-Expressing Microglia that Attenuates Alzheimer Pathology.\u00a0 <\/span><\/a>Mittal K et al., iScience. 2019 Jun 28;16:298-311.\u00a0<\/span><\/li>\n
  8. BDNF-producing, amyloid \u03b2-specific CD4 T cells as targeted drug-delivery vehicles in Alzheimer’s disease.\u00a0 <\/span><\/a>Eremenko E. et al., EBioMedicine. 2019 May;43:424-434.\u00a0<\/span><\/li>\n
  9. The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System.\u00a0 <\/span><\/a>Strominger I. et al., Front Immunol. 2018 May 16;9:1066.\u00a0<\/span><\/li>\n
  10. TGF-\u03b2 affinity-bound to a macroporous alginate scaffold generates local and peripheral immunotolerant responses and improves allocell transplantation.\u00a0 <\/span><\/a>Orr S. et al., Acta Biomater. 2016 Nov;45:196-209.\u00a0<\/span><\/li>\n
  11. Accelerated microglial pathology is associated with A\u03b2 plaques in mouse models of Alzheimer’s disease.\u00a0 <\/span><\/a>Baron R. et al., Aging Cell. 2014 Aug;13(4):584-95.\u00a0\u00a0<\/span><\/li>\n
  12. Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance.\u00a0 <\/span><\/a>Fisher Y. et al., J Immunol. 2014 Jan 1;192(1):92-102.\u00a0<\/span><\/li>\n
  13. Chronic exposure to stress predisposes to higher autoimmune susceptibility in C57BL\/6 mice: glucocorticoids as a double-edged sword.\u00a0 <\/span><\/a>Harpaz I\u00a0 et al., Eur J Immunol. 2013 Mar;43(3):758-69.\u00a0<\/span><\/li>\n
  14. TGF-\u03b2 signaling through SMAD2\/3 induces the quiescent microglial phenotype within the CNS environment.\u00a0 <\/span><\/a>Abutbul S et al., Glia. 2012 Jul;60(7):1160-71.\u00a0<\/span><\/li>\n
  15. HLA-DR alleles in amyloid beta-peptide autoimmunity: a highly immunogenic role for the DRB1*1501 allele.\u00a0 <\/span><\/a>Zota V et al., J Immunol. 2009 Sep 1;183(5):3522-30.\u00a0<\/span><\/li>\n
  16. Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer’s disease.\u00a0 <\/span><\/a>Monsonego A et al., Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5048-53.\u00a0<\/span><\/li>\n
  17. Immunotherapeutic approaches to Alzheimer’s disease.\u00a0 <\/span><\/a>Monsonego A, Weiner HL. Science. 2003 Oct 31;302(5646):834-8. Review.\u00a0<\/span><\/li>\n
  18. Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease.\u00a0 <\/span><\/a>Monsonego A et al., J Clin Invest. 2003 Aug;112(3):415-22.\u00a0<\/span><\/li>\n
  19. Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer’s disease.\u00a0 <\/span><\/a>Monsonego A et al., Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10273-8<\/span><\/li>\n<\/ol>\n[\/vc_column_text][vc_column_text]Click here to see a full list of all of our publications<\/a>[\/vc_column_text][\/vc_column][\/vc_row]\n<\/section>","protected":false},"excerpt":{"rendered":"

    [vc_row][vc_column][vc_column_text] Weight loss aggravates obesity-induced hypothalamic inflammation in mid-aged mice. Zemer A et al., Geroscience. 2025 Oct 17. doi: 10.1007\/s11357-025-01933-x2. CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging. Elyahu Y et al, Nat Aging. 2025 Oct;5(10):1970-1982. doi: 10.1038\/s43587-025-00953-8. CD4 T-cell aging exacerbates neuroinflammation in a late-onset mouse model of amyotrophic lateral sclerosis.\u00a0 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4067","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/pages\/4067","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/comments?post=4067"}],"version-history":[{"count":14,"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/pages\/4067\/revisions"}],"predecessor-version":[{"id":4656,"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/pages\/4067\/revisions\/4656"}],"wp:attachment":[{"href":"https:\/\/fohs.bgu.ac.il\/monsonegolab\/wp-json\/wp\/v2\/media?parent=4067"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}