Dr. Elena Voronov

Dr. Elena Voronov Profile

Researcher B
M.D. 1980, Ph.D. 1988

Department : Shraga Segal Department of Microbiology, Immunology and Genetics
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Phone :
Email : elena@bgu.ac.il
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inflammation, tumor development, angiogenesis, interleukin 1, family molecules

Education

  • M.D. 1980, Ph.D. 1988

Research Interests

  • cancer, immunology, infectious diseases

Research Abstract

  • Research Topics

    • The role of interleukin-1 molecules in colon inflammation and related to colon cancer and colon cancer development
    • Tumor angiogenesis

    Major expertise and techniques in the lab

    • Experiments in vivo
    • Immunohistochemistry
    • Evaluation of the angiogenic response

    Publications and funding summary / representative publications and grants

    • Voronov. E., Shouval, D., Krelin, Y., Cagnano, E., Benhharoch, D., Iwakura, Y., Dinarello, C.A. and Apte, R.N. (2003). IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A, 100: 2645-2650.
    • Carmi, Y., Voronov, E., Dotan, D., Lahat, N., Rahat, M., Fogel, M., Huszar, M., White, M. R., Dinarello, C. A. and Apte R.N. (2009). The role of macrophage-derived IL-1in induction and maintenance of angiogenesis J. Immmunol. 183:4705-14.
    • Voronov, E., Reich, E., Dotan, S., Dransh, P., Cohen, I., Huszar, M., Fogel, M., Kleinman, H.K., White, R.M. and Apte, R.N. (2010). Effects of IL-1 molecules on growth patterns of 3-MCA-induced cell lines: an interplay between immunogenicity and invasive potential. Journal of Immunotoxicology. 7(1):27-38.
    Grant- BSF- Role of IL-1 in myeloid regulatory cell re-polarization in the tumor microenvironment

    Existing collaborations

    • Assaf Rudich
    • Michal Hershfinkel
    • Rachel Lichtenstein

    Suggested multi-disciplinary research project / research focus topics

    • Interleukin-1 biology in health and disease