Prof. Tomer Hertz

Prof. Tomer Hertz Profile

Associate Professor
2007, PhD

Department : Shraga Segal Department of Microbiology, Immunology and Genetics
Room : 101-
בניין המכון הלאומי לביוטכנולוגיה בנגב, ע"ש אדגר דה-פיצ'וטו - 41
Phone : 972-74-7728189
972-74-7728857
972-74-7728856
Email : thertz@post.bgu.ac.il
Office Hours :  
Systems Immunology

Education

B.Sc. Computer Science and an Interdisciplinary Program in the Humanities, The Hebrew
University of Jerusalem, Israel, 1999.
Ph.D. Computational Neuroscience, The Hebrew University of Jerusalem, Israel, 2007.
Title: Learning Distance Functions: Algorithms and Applications.
Advisor: Prof. Daphna Weinshall.

Research Interests

  • Host-pathogen co-evolution through the prism of adaptive immunity
  • Effects of immunological history on responses to natural infection and vaccination
  • Human Leukocyte Antigen (HLA) binding prediction and its applications in vaccine design, HLA-viral interactions, and immunodominance
  • Adjuvant effects on vaccine-induced immunodominance patterns
  • T-cell Sieve analysis of breakthrough infections in vaccine clinical trials

Publications and funding summary / representative publications and grants


  • Stephen R. Walsh, Zoe Moodie, Andrew J. Fiore-Gartland, Cecilia Morgan, Marissa B. Wilck, Scott M. Hammer, Susan P. Buchbinder, Spyros A. Kalams, Paul A. Goepfert, Mark J. Mulligan, Michael C. Keefer, Lindsey R.Baden, Edith M. Swann, Shannon Grant, Hasan Ahmed, Fusheng L, Tomer
     Hertz, Steven G. Self, David Friedrich, Nicole Frahm, Hua-Xin Liao,David C.Montefiori, Georgia D. Tomaras, M. Juliana McElrath, John Hural, Barney S. Graham, Xia Jin, the HVTN 083 Study Group, and the NIAID HIV Vaccine Trials Network. Vaccination with heterologous HIV envelope sequences and heterologous adenovirus vectors increases T cell responses to conserved regions (HVTN 083). Journal of Infectious Diseases. October 2015.

 

 

  • Paul T. Edlefsen*, Morgane Rolland*, Tomer Hertz*, Sodsai Tovanabutra, Andrew J. Gartland, Allan C. deCamp, Craig A. Magaret, Hasan Ahmed, Raphael Gottardo, Michal Juraska, Connor McCoy, Brendan B. Larsen, Eric Sanders-Buell, Chris Carrico, Sergey Menis, Meera Bose, RV144 Sequencing Team, MiguelA. Arroyo, Robert J. O’Connell, Sorachai Nitayaphan, Punnee Pitisuttithum,Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Merlin L. Robb, Tatsiana Kirys, Ivelin S. Georgiev, Peter D. Kwong, Konrad Scheffler, Sergei L. Kosakovsky Pond, Jonathan M. Carlson, Nelson L. Michael, William R. Schief, James I. Mullins, Jerome H. Kim, Peter B. Gilbert. Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial. PLoS Comp. Biol, 11(2): e1003973. doi:10.1371/jour- nal.pcbi.1003973, 2015. 

     

  • Andrew J. Gartland , Sue Li , John McNevin, Georgia D. Tomaras, Raphael Gottardo, Holly Janes, Youyi Fong, Darril D. Morris , Dan E. Geraghty, Gustavo H. Kijak, Paul T. Edlefsen, Nicole Frahm, Branden B. Larsen, Sodsai Tovanabutra, Eric Sanders-Buell, Allan C. deCamp, Craig A. Magaret, Hasan Ahmed, Jodie P. Goodridge, Lennie Chen, Philip Konopa, S. Nariya, Jill N. Stoddard, Kim Wong, Hong Zhao ,Wenjie Deng, Brandon S. Maust, Meera Bose, Shana Howell, Adam Bates, Michelle Lazzaro, Annemarie O’Sullivan, Esther Lei, Andrea Bradfield, Grace Ibitamuno, Vatcharain Assawadarachai, Robert J. O’Connell , Mark S. deSouza, Sorchai Nitayaphan, Supachai Rerks-Ngarm, Merlin L. Robb, John Sidney, Alessandro Sette, Suzan Zolla-Pazner, David Montefiori, M. Juliana McElrath, Jim I. Mullins, Jerome H. Kim, Peter B. Gilbert and Tomer Hertz*. Analysis of HLA A*02 Association with Vaccine Efficacy in the RV144 HIV-1 Vaccine Trial. Journal of Virology, 88(15), 2014.

 

 

 

 

 

 

  • Morgane Rolland, Paul T Edlefsen, Brendan B Larsen, Sodsai Tovanabutra, Eric Sanders-Buell, Tomer Hertz, Allan C DeCamp, Chris Carrico, Sergey Menis, Craig A Magaret, Hasan Ahmed, Michal Juraska, Lennie Chen, Philip Konopa, Snehal Nariya, Julia N Stoddard, Kim Wong, Hong Zhao, Wenjie Deng, Brandon S Maust, Meera Bose, Shana Howell, Adam Bates, Michelle Lazzaro, Annemarie O'Sullivan, Esther Lei, Andrea Bradfield, Grace Ibitamuno, Vatcharain Assawadarachai, Robert J O'Connell, Mark S deSouza, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Merlin L Robb, Jason S McLellan, Ivelin Georgiev, Peter D Kwong, Jonathan M Carlson, Nelson L Michael, William R Schief, Peter B Gilbert, James I Mullins and Jerome H Kim. Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2Nature, 490, 417--420, 2012.

 

 

 

  • Guang Lan Zhang, Hifzur Rahman Ansari, Phil Bradley, Gavin C Cawley, Tomer Hertz, Xihao Hu, Nebojsa Jojic, Yohan Kim, Oliver Kohlbacher, Ole Lund, Claus Lundegaard, Craig A Magaret, Morten Nielsen, Harris Papadopoulos, G P S Raghava, Vider-Shalit Tal, Li C Xue, Chen Yanover, Shanfeng Zhu, Michael T Rock, James E Crowe Jr., Christos Panayiotou, Marios M Polycarpou, Wlodzisaw Duch and Vladimir Brusic. Machine learning competition in immunology -- Prediction of HLA class I binding peptides, Journal of immunological methods, 374, 1--4, 2011.

 

 

 

 

 

 

 

 

  • Rubi Hammer, Tomer Hertz, Shaul Hochstein and Daphna Weinshall. Classification with Positive and Negative Equivalence onstraints: Theory, Computation and Human ExperimentsBVAI, 264-276, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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