Dr. Levaot Noam

Dr. Levaot Noam Profile

Senior lecturer
Ph.D., 2008

Department : Physiology and Cell Biology
Room : 318
בנין מעבדות מחקר רפואה ע"ש דייכמן - פלאם
Phone : 972-8-6477304
Email : levaot@bgu.ac.il
Office Hours :  
bone metabolism, osteoporosis, bone diseases, genome editing


  • Ph.D. 2008

Research Topics

  • The Molecular and cellular basis of bone in health and disease
  • Cell biology of bone cells
  • Bone cell-matrix mediated signaling
  • CRISPR mediated genome editing

Major expertise and techniques in the lab

  • Bone metabolism
  • Live imaging microscopy
  • Biochemistry and molecular biology

Publications and funding summary / representative publications and grants

  • Levaot et al. Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism. Cell, 2011; 147:1324-1339.
  • Levaot et al. 3BP2 deficient mice are osteoporotic with impaired osteoblast and osteoclast functions. J clin invest. 2011; 121:3244-3257.

Existing collaborations

  • Benjamin Geiger - Regulation of osteoclast fusion
  • Niv Papo - protein engineering to generate novel drugs for skeletal diseases. 
  • Michal Hershfinkel - Zinc signaling in bone cells
  • Bjorn Busse - GPR39 regulation of bone composition 

Suggested multi-disciplinary research project / research focus topics

  • Cell signaling in bone cells
  • Skeletal phenotyping
  • animal models for skeletal diseases 
  • Blood biochemical markers of bone diseases
  • Generation of animal models for human diseases