Senior lecturer
Ph.D., 2008
bone metabolism, osteoporosis, bone diseases, genome editing |
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- The Molecular and cellular basis of bone in health and disease
- Cell biology of bone cells
- Bone cell-matrix mediated signaling
- CRISPR mediated genome editing
Major expertise and techniques in the lab
- Bone metabolism
- Live imaging microscopy
- Biochemistry and molecular biology
Publications and funding summary / representative publications and grants
- Levaot et al. Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism. Cell, 2011; 147:1324-1339.
- Levaot et al. 3BP2 deficient mice are osteoporotic with impaired osteoblast and osteoclast functions. J clin invest. 2011; 121:3244-3257.
- Benjamin Geiger - Regulation of osteoclast fusion
- Niv Papo - protein engineering to generate novel drugs for skeletal diseases.
- Michal Hershfinkel - Zinc signaling in bone cells
- Bjorn Busse - GPR39 regulation of bone composition
Suggested multi-disciplinary research project / research focus topics
- Cell signaling in bone cells
- Skeletal phenotyping
- animal models for skeletal diseases
- Blood biochemical markers of bone diseases
- Generation of animal models for human diseases