Prof. Dan Levy

Prof. Dan Levy Profile

Associate Professor
PhD, 2008

Department : Shraga Segal Department of Microbiology, Immunology and Genetics
Room : 102
בנין 41 - המכון הלאומי לביוטכנולוגיה בנגב
Phone : 972-8-6477252
972-74-7728853
972-8-6477251
Email : ledan@post.bgu.ac.il
Office Hours :  
Lysine methylation signaling and epigenetics

Education

    • Postdoctoral fellow:
      Stanford University, Stanford, CA, USA
      Department of Biology, Advisor: Prof. Or Gozani. Epigenetic and Chromatin
    • Weizmann Institute of Science, Israel Department of molecular Genetics, Advisor: Prof. Yosef Shaul.
      Decision making mechanisms for DNA-damage signaling
    • Tel Aviv University, Israel
      Department of Human Genetics and Molecular Medicine, Advisor: Prof. Gil Ast.
    • 1998-2001 B.Sc with Honors, Plant Science, the Hebrew University, Faculty of Agriculture, Jerusalem, Israel
      Major subjects:
      Agriculture, plant genetics and biotechnology.

Research Interests

  • The goal of our research is to understand how lysine methylation through epigenetics mechanisms regulates oncogenic and cell differentiation processes.
  • We apply biochemical, cellular, genomic and proteomics approaches to address fundamental questions in the intersection between chromatin biology and cell signaling.

Research Projects

  • To characterize the biochemical and biological functions of SETD6
  • To define the role of lysine methylation in modulating in a variety of biological processes and disease models, with the focus on oncogenic and cell differentiation processes.
  • To identify new methylation on histone and non-histone proteins; define the molecular mechanisms by which these methyl marks are generated and transduced; to unravel the biological functions of the methylation events.
  • To further develop peptide and protein microarrays technologies focusing on protein lysine methylation.

Major expertise and techniques in the lab

  • ChiP
  • Methylation assays

Additional links