Dr. Alex Braiman

Dr. Alex Braiman Profile

Senior lecturer
Ph.D, 2001

Department : Shraga Segal Department of Microbiology, Immunology and Genetics
Room : 220
בנין מעבדות מחקר רפואה ע"ש דייכמן - פלאם - M6
Phone : 972-8-6477289
972-8-6477250
Email : braiman@bgu.ac.il
Office Hours :  
immunology, genetics, signal transduction, confocal microscopy, imaging, calcium, senescence, cancer

Education

  • Ph.D. 2001

Research Interests

  • T cell activation, calcium signaling
  • fluorescent microscopy
  • imaging, high-resolution optical microscopy

Research Topics

  • Signal transduction in lymphocytes
  • Protein-protein interactions
  • Intercellular signaling between senescent and cancer cells

Major expertise and techniques in the lab

  • Confocal microscopy and advanced microscopy techniques
  • Calcium signaling

Publications and funding summary / representative publications and grants

  • Knyazhitsky M, Moas I, Shaginov E., Luria A, Braiman A . The oncogenic mutation of Vav1 inhibits the T cell receptor induced calcium mobilization through inhibition of phospholipase C g 1 activation. Journal of Biological Chemistry , 287(3): 19725-35, 2012.

Existing collaborations

  • Prof. A. Porgador – NK receptors and immunological synapses
  • Prof. V. Fraifeld and Prof. M. Wolfson – interactions between senescent and malignant cells

Suggested multi-disciplinary research project / research focus topics

  • Cellular physiology, biophysics
  • Inter- and intracellular communication