Dr. Abed N. Azab

Dr. Abed N. Azab Profile

Senior lecturer
Ph.D, 2003

Researcher

Department : Clinical Biochemistry and Pharmacology
Recanati School for Community Health Professions
Nursing
Room : 667
אשפוז פנימיות-קומה 6
Phone : 972-8-6479862
Email : azab@bgu.ac.il
Office Hours :  
Clinical Pharmacology, Psychopharmacology, Nursing

Education

  • 1993-1996; B.N., Department of Nursing, Ben-Gurion University of the Negev
  • 1997-1998; M.Sc., Department of Clinical Pharmacology, Ben-Gurion University of the Negev
  • 1999-2003; Ph.D., Department of Clinical Pharmacology, Ben-Gurion University of the Negev
  • Professional Training
    2004-2006, Post-doctoral Fellow, Department of Biological Sciences, Wayne State University; Detroit (MI), USA
  • 2007-2008, Post-doctoral Fellow, Departments of Nursing & Clinical Pharmacology, Ben-Gurion University of the Negev
  • 2007, Clinical Instructor, School for Community Health Professions, Department of Nursing, Ben-Gurion University of the Negev

Research Topics

  • Effect of psychotropic drugs on brain inflammation
  • Role of GSK-3 in the mechanisms underlying mood disorders
  • Psychiatric and cardiovascular nursing

Major expertise and techniques in the lab

  • In-vitro, ex-vivo and in-vivo models of inflammation & examination of the effect of drugs
  • Nursing precautions and considerations in pharmacotherapy

Publications and funding summary / representative publications and grants

  • Nahman S, Belmaker RH, Azab AN (2012). Effects of lithium on lipopolysaccharide-induced inflammation in rat primary glia cultures. Innate Immunity, 18: 447-58.
  • Bloch Y, Appelbaum J, Osher Y, Samuel S, Azab AN, Agam G, Belmaker RH, Bersudsky Y (2012). Normobaric Hyperoxia Treatment of Schizophrenia. Journal of Clinical Psychopharmacology, 32: 525-30.          
  • Boyko M^, Azab AN^, Kuts R, Gruenbaum BF, Gruenbaum SE, Melamed I, Brotfain E, Shapira Y, Cesnulis E, Zlotnik A (2013). The neuro-behavioral profile in rats after subarachnoid hemorrhage. Brain Research, 1491: 109-16. ^ Equally contributed
  • Nassar A, Azab AN (2014). Effects of lithium on inflammation. ACS Chemical Neuroscience, 5:451-58
  • Damri O, Sade Y, Toker L, Bersudsky Y, Belmaker RH, Agam G^, Azab AN^ (2015). Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner. European Neuropsychopharmacology, 25: 425-34. ^ Co-corresponding authors.   
  • Azab AN, Shnaider A, Osher Y, Wang D,  Bersudsky Y, Belmaker RH (2015). Lithium nephrotoxicity. International Journal of Bipolar Disorder; 3 (1):28. doi: 10.1186/s40345-015-0028-y.
  • Boyko M, Nassar A, Kaplanski J, Zlotnik A, Sharon-Granit Y, Azab AN (2015). Effects of acute lithium treatment on cytokines and prostaglandin E2 levels in post-stroke rats. BioMed Research International; 2015:916234. doi: 10.1155/2015/916234.                   
  • Faour-Nmarne C, Azab AN (2016). Effects of olanzapine on lipopolysaccharide-induced inflammation in rat primary glia cultures. Innate Immunity, 18: 447-58.

Existing collaborations

  • Yuly Bersudsky, Galila Agam and Haim Belmaker – Understanding the Mechanisms Underlying the Therapeutic Efficacy of Psychotropic Drugs
  • Matthew Boyko and Alexander Zlotnik – Involvement of Inflammation in the Pathophysiology of Ischemic Stroke.

Suggested multi-disciplinary research project / research focus topics

  • Psychotropic drugs and brain inflammation
  • Nursing precautions and considerations in pharmacotherapy