Prof. Jacob Gopas

Prof. Jacob Gopas Profile

Professor
PH.D. 1982, MPH 1997
Residency: None

Head of Department

Department : Shraga Segal Department of Microbiology, Immunology and Genetics
Room : 228
בנין מעבדות מחקר רפואה ע"ש דייכמן - פלאם - M6
Phone : 972-8-6477255
972-8-6477253
Email : jacob@bgu.ac.il
Office Hours :  
cancer, lymphoma, melanoma, plants

Education

  • Albert Einstein College of Medicicine, Bronx NY, USA. (Ph.D.) 1971-1975 B.Sc Microbiology, Bar-Ilan University Ramat-Gan, Israel 1975-1977 M.Sc. Dept. of Microbiology, Bar-Ilan University, Ramat-Gan, Israel with Prof. Arye Rozenszajn. Thesis: “The influence of hemopoietic cell factors on colony forming lymphocytes in agar culture.” 1977-1982 Ph.D. Dept of Cell Biology, Albert Einstein College of Medicine, New York with Dr. Stanley G. Nathanson. Thesis: “In-vitro selection and characterization of an MHC variant carrying an altered H-2Kb gene product.” 1982-1983 Post-doctoral work, Dept. of Microbiology & Immunology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. With Prof. Shraga Segal. 1994-1997 Master in Health Management. Dept. of Industry and Management Engineering. Ben-Gurion University, Beer-Sheva, Israel

Research Interests

Detection and characterization of anti-cancer, anti-inflammatory and anti-viral products from natural sources based on the inhibition of NF-kB.
Biology of Hodgkin's lymphoma
Mechanisms of drug resistance human melanoma cell-lines.
microRNAs in viral persistent infection

Pediatric Sleep Apnea

Research Topics

  • Isolation and characterization of natural anti-cancer, anti-inflammatory and antiviral products from plants and marine bacteria
  • The role of microRNAs in viral persistent infection
  • Pathogenesis of pediatric obstructive sleep apnea

Major expertise and techniques in the lab

  • Cellular and Molecular biology of cancer and inflammation
  • Cellular and Molecular biology of measles and RSV viruses
  • In vivo cancer, inflammation and virology models

Publications and funding summary / representative publications and grants

  • Publications and recent grants 75 peer reviewed papers (21 Q1, 19 Q2, 14 Q3, 6 Q4, 15 not defined). Recent Grants: 2011-2013 Israel Ministry of Health. "Anti-cancer and anti-inflammatory properties of Nupharidine" with Prof. Avi Golan 2012-2014 NIH RO3 AI94164-01A1. "The role of host-encoded microRNAs in maintaining measles virus persistence" PI with Dr. Glenn Rall (Fox Chase Cancer Institute, Philadelphia, USA)

Existing collaborations

  • Prof. Avi Golan and Dr. Ariel Kushmaro- Isolation and characterization of natural anti cancer, anti-inflammatory and antiviral products from plants
  • Prof. Glenn Rall, Prof. Zvi Bentwich and Dr. Yonat Shemer- The role of microRNAs in viral persistent infection
  • Prof.. Aviv Goldbart-Pathogenesis of pediatric obstructive sleep apnea
  • Prof. Etta Livneh, Prof. Siddharth Balachandran and Prof. Dany Benharroch. Cell Senescence in Hodgkin's lymphoma

     

Looking for expertise / project

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