Prof. Yael Segev

Prof. Yael Segev Profile

Professor


Department : Shraga Segal Department of Microbiology, Immunology and Genetics
Room : 120
בנין דייכמן למקצועות הבריאות - M8
Phone : 972-8-6479537
Email : yaelse@bgu.ac.il
Office Hours :  

Education

  • Ph.D. 1993

Research Topics

  • Chronic kidney disease related growth retardation
  • GH and IGF-1 signaling
  • Sleep disordered breathing related growth retardation

Major expertise and techniques in the lab

  • Animal experimentation
  • In vivo hormone mediated signaling pathway assessment

Publications and funding summary / representative publications and grants

  • Tarasiuk A, Berdugo-Boura N, Troib A, Segev Y . Role of GHRH in sleep and growth Impairments Induced by upper airway obstruction in rats. Eur Resp J 38:870-7;2011.
  • Landau D, Eshet R, Troib A, Gurman Y, Yu Chen, Rabkin R, Segev Y . Increased renal Akt / mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation. Endocrine 36:126-34;2009.
  • Grants: US-Israel Binational Science Foundation (BSF) (X2); Israeli Science Foundation (ISF) (X2)

Existing collaborations

  • Daniel Landau, M.D.(BGU) and Ralph Rabkin , MD (Stanford Univ.) : The local bone GHR signaling in CKD related growth retardation and its modulation by diet and exercise.
  • Ariel Tarasiuk , Ph.D (BGU): Growth retardation following chronic resistive airway loading in rats : interactions between sleep disruption and GH/IGF-1 axis .
  • Esther Priel , Ph.D (BGU): The influence of type I diabetes on DNA Topoisomerase I and Telomerase in animal models

Suggested multi-disciplinary research project / research focus topics

  • Growth retardation related to chronic disorders in childhood: looking for common pathways
  • The impact of uremia on long bone development and hematopoetic stem cell (HSC) niche formation using a fetal bone implant model.

Looking for expertise / project

  • European partner with common research interests