Prof. Orian Shirihai

Prof. Orian Shirihai Profile

Professor
MD, PhD 1997

Adjunct Professor

Department : Clinical Biochemistry and Pharmacology
Room :
Phone :
Email : shirihai@bgu.ac.il
Office Hours :  
Mitochondrial dynamics, metabolic diseases

Education

  • Ph.D.: Technion, Israel
  • Post-doctoral fellowship: Harvard University School of Medicine

Research Interests

  • Mitochondrial dynamics
  • Metabolic diseases

Publications and funding summary / representative publications and grants

  • Twig G., Elorza A., Molina A.J., Mohamed H., Wikstrom J.D., Walzer G., Stiles L., Haigh S.E., Katz S., Las G., Alroy J., Wu M., Py B.F., Yuan J., Deeney J.T., Corkey B.E. and Shirihai O.S. (2008). Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 27:433-446.
  • Molina A.J., Wikstrom J.D., Stiles L., Las G., Mohamed H., Elorza A., Walzer G., Twig G., Katz S., Corkey B.E. and Shirihai O.S. (2009). Mitochondrial networking protects beta-cells from nutrient-induced apoptosis. Diabetes 58:2303-2315.
  • Las G., Sereda S., Wikstrom J.D., Twig G., and Shirihai O.S. (2011). Fatty acids suppress autophagic turnover in cells. J. Biol. Chem. 286:42534-42544.
  • Liesa M. and Shirihai O.S. (2013). Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metabolism 17:491-506.
  • Wikstrom J.D., Mahdaviani K., Liesa M., Sereda S.B., Si Y., Las G., Twig G., Petrovic N., Zingartti C., Graham A., Cinti S., Corkey B.E., Cannon B., Nedergaard J. and Shirihai O.S. (2014). Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO Journal 33(5):418-436.