Genome Variation: The Differences between us

The average difference between two human genomes is roughly 0.1 percent. Inside these variations is all of the genetics that contribute to the variety between us - and many of the roots of what ails each of us.

Learning resources

• Study Guide
• Wall and Pritchard (2003) Haplotype blocks and linkage disequilibrium in the human genome
• Conrad et al (2006) A worldwide survey of haplotype variation and linkage disequilibrium in the human genome
• Vittori et at (2014) Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington’s disease
• Prüfer et al (2017) A high-coverage Neandertal genome from Vindija Cave in Croatias
• Hu et al (2023) Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition
• Dutta et al (2017) Intricacies in arrangement of SNP haplotypes suggest “Great Admixture” that created modern humans
• Narration: Human Genome Variation